Shabbir Ansari, PhD
3 Blackfan Circle, Room 924
Boston, MA 02115
sansari1@bidmc.harvard.edu
Shabbir obtained his PhD degree from Calcutta University, India in collaboration with University of Texas Health Science Center at Tyler, Texas. His thesis focused on understanding the cellular and molecular mechanisms of tissue factor (TF) decryption/activation. Shabbir joined the Schulman lab to further his understanding of TF-mediated thrombosis in various pathological conditions such as sepsis and COVID-19 using primary cell cultures, murine models and clinical samples. Outside the lab, Shabbir likes to spend time with his family and friends. Last but not the least, Shabbir is a rusty but passionate cricketer.
Marisa Brake, PhD
3 Blackfan Circle, Room 924
Boston, MA 02115
mbrake@bidmc.harvard.edu
Marisa obtained her PhD in Biomedical Sciences from Oakland University in Michigan. She joined Dr. Sol Schulman’s lab under the support of the T-32 training program. Marisa’s research focus is on understanding the regulation of tissue factor by utilizing mouse models, cell lines, and human samples and how those factors contribute to thrombosis and hemostasis.
Keiichi Enjyoji, PhD
3 Blackfan Circle, Room 924
Boston, MA 02115
kenjoji@bidmc.harvard.ed
Keiichi obtained his PhD from Kyushu University in Japan in biochemistry. He has been working on two projects: 1) the genes which might be involved in tissue factor turnover and stability, and 2) analysis of virus-induced coagulopathy and therapeutic application of novel drugs to treat coagulopathy of sepsis, using in vivo and in vitro systems. Previously he worked on the role of cd39/ENTPDase1 in metabolic disease such as atherosclerosis, diabetes and inflammation at BIDMC.
Allison Gabbert, PhD
3 Blackfan Circle, Room 924
Boston, MA 02115
Agabbert@bidmc.harvard.edu
Allison earned her PhD in Molecular, Cellular, and Developmental Biology from the University of California, Santa Barbara. Her thesis involved studying how the cytoskeleton alters the cell membrane during collective cell migration. Allison’s research in the Schmaier lab focuses on the functions of TMEM phospholipid scramblases in vascular endothelial cells during inflammation and thrombosis.
Shihui Guo, PhD
3 Blackfan Circle, Room 924
Boston, MA 02115
sguo3@bidmc.harvard.edu
Shihui received his Ph.D. in Molecular Biology from Salzburg University and initially joined the Flaumenhaft lab as a postdoctoral research fellow with a CSC Scholarship. Currently, he is applying cell and molecular biology techniques to evaluate the molecular mechanisms of protein disulfide isomerase underlying thrombus formation. Additionally, Shihui has had successful collaborations with physician-scientists and research experts on both inter-and intra-organizational teams. He has also expanded his role as a meeting organizer for the Division, a mentor for the young partners, and a reviewer for scientific journals in the field.
Ivan Hancco Zirena, MD, PhD
3 Blackfan Circle, Room 924
Boston, MA 02115
ihanccoz@bidmc.harvard.edu
Ivan studied medicine at the Universidad Nacional del Altiplano of Puno in Peru. He completed residency training in Hematology at Daniel Alcides Carrion Hospital of Callao Peru and completed his master’s studies in Integrated Biology and Physiology at the Claude Bernard University of Lyon, France. He obtained a PhD from the Grenoble Alpes University in France. He joined Dr. Flaumenhaft´s laboratory and his research program is focused on the mechanism of thiol isomerases in thrombosis.
Jacob Ludington, MD, PhD
3 Blackfan Circle, Room 924
Boston, MA 02115
jludingt@bidmc.harvard.edu
Jacob received his MD, PhD from Tufts University School of Medicine where he studied molecular mechanisms underlying host-pathogen interactions and their role in disease. His interest in hematology led to him joining the Schulman lab to investigate viral processes contributing to COVID-19-associated coagulopathy and perturbations in exosome biogenesis and release.
Glenn Merrill-Skoloff, B.S.
Glenn is a New England native having been born and raised in Pigeon Cove, Massachusetts. In 1993, he recived a Bachelor of Science degree in Biochemistry from the University of Massachusetts at Amherst. He joined the Division of Hemostasis and Thrombosis at New England Medical Center in 1995, migrating to the Beth Israel Deaconess Medical Center when the division relocated in 1999. Since moving to BIDMC, his focus has been studying thrombosis using intravital microscopy and a laser ablation injury model in the cremaster muscle of mice. This technique was developed, in part, by Glenn who is currently the Director of the Intravital Microscopy Core Facility as well as the Laboratory Manager for the division.
Ronodeep Mitra, PhD
3 Blackfan Circle, Room 924
Boston, MA 02115
rmitra1@bidmc.harvard.edu
Ronodeep earned his PhD in Chemical Engineering from Northeastern University. His thesis involved developing preventative therapies for atherosclerosis targeting the glycocalyx to reverse endothelial dysfunction. He is currently in the Schmaier Lab investigating how the vascular endothelium regulates procoagulant activity during systemic inflammation and thrombosis. He plans on pursuing a career in cardiovascular medicine.
Zach Schoepflin, MD, PhD
3 Blackfan Circle, Room 924
Boston, MA 02115
zschoepf@bidmc.harvard.edu
Zach graduated from Thomas Jefferson University with his MD and PhD in cell biology and regenerative medicine. He is currently a resident in internal medicine at BIDMC. His research in the Schulman lab is focused on using high-throughput approaches to identify FDA-approved compounds that have off-target effects on tissue factor activity.
Dr. Arjun Sharma, PhD, MBA
Center for Life Sciences Building, CLS-924
3 Blackfan Circle, Boston, MA 02115
arjunyug@bidmc.harvard.edu
Dr. Arjun Sharma is a Ruth L. Kirschstein NRSA T32 Postdoctoral Research Scientist in the Blood Coagulation and Vascular Biology Program at Harvard Medical School and Beth Israel Deaconess Medical Center, where he works with Professor Robert Flaumenhaft, Chief of the Division. He holds a PhD in Translational Medicine from Universitätsmedizin, Johannes Gutenberg University Mainz (Germany), an MBA in Health Sector Management from Boston University (USA), and an MS in Biotechnology from VIT University Vellore (India) and the National University of Singapore (Singapore).
Alumni Post-Docs
Ivan Aivasovsky, MD
Dr. Ivan Aivasovsky is a Venezuelan Physician who graduated in Bogotá, Colombia with an emphasis in Public Health. His research has been focused on Cardiovascular Healthcare, Health Promotion, and Clinical Research. Especially interested in pursuing a career as a Cardiologist, he worked as a Postdoctoral Research Fellow under the mentorship of Dr. Alec Schmaier.
David A. Barrios, PhD
David is a native of Chicago and is an avid fan of both the Cubs and Red Sox. After serving honorably in the U.S. Navy, David went on to receive his B.S. in Chemistry from the University of Illinois at Urbana-Champaign in 2008 and his Ph.D. in Chemistry from North Carolina State in 2013. His research in this lab focused on lateral flow assay development for screening the efficacy of antiplatelet therapies as well as exploring the role of PDI in hemostasis and thrombosis.
Karen De Ceunynck, PhD
Karen is originally from Belgium where she received her Master’s degrees in Biomedical Sciences and Molecular Biotechnology from Ghent University and her PhD in Biochemistry & Biotechnology from the Catholic University of Leuven. Her research has been focused on understanding processes involved in hemostasis and thrombosis and using that knowledge to guide the development of novel therapeutics. She previously worked on conducting translation research to evaluate how endothelial therapies can reduce uncontrolled blood clotting in the setting of infectious disease.
Awards:
2015 – Young Investigator Award – International Society on Thrombosis and Haemostasis
2016 to Present – NIH T32 Training Grant
2016 – Translational Research Training in Hematology (TRTH) – Joint EHA and ASH award
2016 – Abstract Achievement Award – American Society of Hematology (ASH)
2017 – Young Investigator Award – International Society on Thrombosis and Haemostasis
Maneli Doroudian, MD
Maneli was a postdoctoral research fellow who joined the Flaumenhaft lab in 2018, to study the critical role of the endothelial Angiopoietin-Tie2 pathway in thrombosis. She grew up in Tehran then moved to Boston, after completing her medical school and working as a physician for a couple of years. Outside of the lab, Maneli is a nature and art enthusiast, enjoys spending time with family and friends, along with traveling.
Oskar Eriksson, MD, PhD
Oskar received his MD and PhD from the University of Uppsala in Sweden. His PhD thesis focused on experimental and translational studies on cell signaling by coagulation proteases in the context of cancer. Oskar joined the lab in 2016 and worked on understanding the role of extracellular thiol isomerases in the initiation of plasma cascade systems during thromboinflammation.
Awards:
2016 to 2018 – International Post Doctoral Fellowship – Swedish Research Council
Sarah Higgins, PhD
Sarah was previously a postdoctoral research fellow who joined the Flaumenhaft lab to study the critical role of the endothelial angiopoietin-Tie2 pathway in thrombosis, as an extension of the collaborative partnership between the Division of Thrombosis and Hemostasis and Center for Vascular Biology Research at BIDMC. Overall, Sarah’s work aimed to apply basic molecular research to tackle unmet global health needs, with a specific focus on vascular biology in the setting of infection, thrombosis and inflammation. Sarah received her B.Sc. in Forensic Science from Trent University and PhD in Laboratory Medicine from the University of Toronto where her work at the Sandra Rotman Centre for Global Health led to a patented host-targeted treatment intervention for cerebral malaria developed in collaboration with industry partners. Outside the lab, Sarah is an avid runner and nature enthusiast who can often be found exploring NE’s many incredible mountains and craft breweries.
Awards:
Frederick Banting and Charles Best Canada Graduate Scholarships CIHR Doctoral Award
2016 – 2018 – American Heart Association Postdoctoral Research Fellowship Founders Affiliate Award
Lin Lin, PhD
Oluwatoyosi Muse, PhD
Oluwatoyosi graduated from Binghamton University with her PhD in Chemistry. Her research is focused on evaluating the effects of protein disulfide inhibitors on platelet function and thrombin generation in clinical samples from patients with solid tumors and myeloproliferative neoplasm.
Awards:
2019 Mary Rodes Gibson Memorial Award in Hemostasis and Thrombosis
Natasha Panwar, MD
Natasha grew up in India and received her medical training from prestigious Lady Hardinge Medical College, New Delhi. After completion of her medical training, she worked as physician in India for couple of years and later moved to the United States. She worked on tissue factor under mentorship of Dr. Sol Schulman. Natasha is also an experienced hiker and has hiked many major peaks in New England.
Christian Peters, PhD
Christian received his Bachelor of Science at Bethany College in West Virginia. Afterwards he received his Master’s degree at the Indiana University of Pennsylvania and his PhD in Biomedical Sciences from the University of Toledo. His research interests have been focused on the cellular and molecular basis of peptide and protein secretion. He conducted research in this lab to demonstrate the movement of distinct populations of alpha-granules in platelets. Additionally, a portion of his research was focused on endothelial responses to various small molecules.
Justine Ryu, MD
Jack Stopa, PhD
Noppacharn Uaprasert, MD
Noppacharn is originally from Bangkok, Thailand. He received Doctor of Medicine and certified Board of Hematology from Chulalongkorn University. He is a faculty member at Division of Hematology, Department of Medicine, Faculty of Medicine, Chulalongkorn University. He received a two-year scholarship from Anandamahidol Foundation between 2016-2018 to study in advanced basic science research. His research was focused on thalassemia and hemoglobinopathies as well as hemostasis and thrombosis. His research in this lab were focused on mechanisms of protein disulfide isomerase in regulation of platelet functions and hemostasis and thrombosis models in mice with hemostatic defects.
Awards:
2017 – Abstract Achievement Award – American Society of Hematology (ASH)
